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Active Pharmaceutical Ingredients

Grindeks is a No 1 choice as a worldwide APIs supplier due to our commitment to quality, modern manufacturing units and global regulatory accreditation. APIs are produced according to GMP requirements, certified by Authorization (licence) for API manufacturing and Certificate of GMP compliance of manufacturer.

A-Z
Antazoline phosphate
  • INN

    Antazoline phosphate

  • Therapeutic use

    Antihistaminic

  • Quality application

    USP ASMF (Active Substance Master File)

  • CAS number

    154-68-7

  • Status

    Under Contractmanufactring

  • Usage

    For human use

  • Chemical name

    NBenzyl-N(4,5-dihydro-1Himidazol-2-ylmethyl)aniline phosphate

  • Molecular formula

    C17H19N3 • H3PO4

  • Molecular weight

    363.35

  • Structure

Atipamezole hydrochloride
  • INN

    Atipamezole hydrochloride

  • Therapeutic use

    Antidote to a2-adrenoceptor induced sedation (vet.)

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File) USP VMF Complete Document

  • CAS number

    104075-48-1

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole hydrochloride

  • Molecular formula

    C14H16N2 • HCl

  • Molecular weight

    248.76

  • Structure

Bortezomib
  • INN

    Bortezomib

  • Therapeutic use

    Proteasome inhibitor

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    179324-69-7

  • Status

    Under developemnt

  • Usage

    For human use

  • Chemical name

    [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid

  • Molecular formula

    C19H25BN4O4

  • Molecular weight

    384.24

  • Structure

Dasatinib
  • INN

    Dasatinib

  • Therapeutic use

    Tyrosine kinase inhibitor

  • Quality application

    Under developemnt

  • CAS number

    302962-49-8

  • Status

    Under developemnt

  • Usage

    For human use

  • Chemical name

    N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)- 1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazole carboxamide

  • Molecular formula

    C22H26CIN7O2S

  • Molecular weight

    488.01

  • Structure

Desaminooxytocin
  • INN

    Desaminooxytocin

  • Therapeutic use

    Uterotonic

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    113-78-0

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    1-(3-Mercaptopropanoic acid)oxytocin

  • Molecular formula

    C43H65N11O12S2

  • Molecular weight

    992.19

  • Structure

Detomidine hydrochloride
  • INN

    Detomidine hydrochloride

  • Therapeutic use

    Sedative (vet.)

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File) USP VMF Complete Document

  • CAS number

    90038-01-0

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    4-[(2,3-Dimethylphenyl)methyl]-1H-imidazole hydrochloride

  • Molecular formula

    C12H14N2 • HCl

  • Molecular weight

    222.72

  • Structure

Dexmedetomidine hydrochloride
  • INN

    Dexmedetomidine hydrochloride

  • Therapeutic use

    Sedative, analgesic

  • Quality application

    USP and Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    145108-58-3

  • Status

    Commercially available

  • Usage

    For human and veterinary use

  • Chemical name

    4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride

  • Molecular formula

    C13H16N2 • HCl

  • Molecular weight

    236.74

  • Structure

Droperidol
  • INN

    Droperidol

  • Therapeutic use

    Neuroleptic

  • Quality application

    Ph.Eur. CEP (Certificate of Suitability), Ph.Eur. ASMF (Active Substance Master File), USP ASMF (Active Substance Master File)

  • CAS number

    548-73-2

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-2-=1,3-dihydro-2H-benzimidazol-2-one

  • Molecular formula

    C22H22FN3O2

  • Molecular weight

    379.43

  • Structure

Imatinib mesilate
  • INN

    Imatinib mesilate

  • Therapeutic use

    Tyrosine kinase inhibitor, antineoplastic

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    220127-57-1

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]= phenyl]benzamide methanesulfonate

  • Molecular formula

    C29H31N7O • CH4SO3

  • Molecular weight

    589.70

  • Structure

Medetomidine hydrochloride
  • INN

    Medetomidini hydrochloride

  • Therapeutic use

    Sedative, analgesic (vet.)

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File) USP VMF Complete Document

  • CAS number

    86347-15-1

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride

  • Molecular formula

    C13H16N2 HCl

  • Molecular weight

    236.74

  • Structure

Oxytocin
  • INN

    Oxytocinum

  • Therapeutic use

    Uterotonic

  • Quality application

    Ph.Eur. CEP (Certificate of Suitability) Ph.Eur. ASMF (Active Substance Master File) USP ASMF (Active Substance Master File) USP VMF Complete Document

  • CAS number

    50-56-6

  • Status

    Commercially available

  • Usage

    For human and veterinary use

  • Chemical name

    L-Cysteinyl-L-Tyrosyl-L-Isoleucyl-L-Glutaminyl-=L-Asparaginyl-L-Cysteinyl-L-Prolyl-L-Leucylglycinamide cyclic (1->6) disulfide

  • Molecular formula

    C43H66N12O12S2

  • Molecular weight

    1007.20

  • Structure

Pemetrexed disodium
  • INN

    Pemetrexed disodium

  • Therapeutic use

    Antineoplastic

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File) under development

  • CAS number

    150399-23-8

  • Status

    Under development

  • Usage

    For human use

  • Chemical name

    N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt

  • Molecular formula

    C20H19N5Na2O6

  • Molecular weight

    471.37

  • Structure

Pimobendan
  • INN

    Pimobendan, Pimobendanum (in Latin)

  • Therapeutic use

    Cardio Vascular (vet.)

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    74150-27-9

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    6-[2-(4-Methoxyphenyl)-3H-benzimidazol-5-yl]-5-methyl-4,5-dihydro-2H-pyridazin-3-one

  • Molecular formula

    C19H18N4O2

  • Molecular weight

    334.37

  • Structure

Rilmenidine dihydrogen phosphate
  • INN

    Rilmenidini dihydrogenphosphas

  • Therapeutic use

    Antihypertensive

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    85409-38-7

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    N-(Dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine dihydrogen phosphate

  • Molecular formula

    C10H16N2O • H3PO4

  • Molecular weight

    278.24

  • Structure

Solifenacin succinate
  • INN

    Solifenacin succinate

  • Therapeutic use

    Antimuscarinic

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File) under development

  • CAS number

    242478-38-2

  • Status

    Under development

  • Usage

    For human use

  • Chemical name

    (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic acid (3R)-1-azabicyclo-[2.2.2]oct-3-yl ester succinate

  • Molecular formula

    C23H26N2O2 • C4H6N2O4

  • Molecular weight

    480.55

  • Structure

Sunitinib
  • INN

    Sunitinib

  • Therapeutic use

    Receptor tyrosine kinase inhibitor

  • Quality application

    API is under development

  • CAS number

    341031-54-7

  • Status

    Under development

  • Usage

    For human use

  • Chemical name

    N-(2-diethylaminoethyl)-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide

  • Molecular formula

    C19H25BN4O4

  • Molecular weight

    398.48

  • Structure

Tegafur (Ftorafur)
  • INN

    Tegafur

  • Therapeutic use

    Cytostatic

  • Quality application

    JP/Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    17902-23-7

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-(1H,3H)-pyrimidinedione

  • Molecular formula

    C8H9FN2O3

  • Molecular weight

    200.17

  • Structure

Tioguanine
  • INN

    Tioguanine

  • Therapeutic use

    Cytostatic

  • Quality application

    BP ASMF (Active Substance Master File)

  • CAS number

    154-42-7

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    2-Amino-1,7-dihydro-6H-purine-6-thione

  • Molecular formula

    C5H5N5S

  • Molecular weight

    167.19

  • Structure

Ursodeoxycholic acid
  • INN

    Ursodeoxycholic acid

  • Therapeutic use

    Anticholelithogenic

  • Quality application

    Ph.Eur. CEP (Certificate of Suitability), Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    128-13-2

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    4-(3,7-Dihydroxy-10,13-dimethyl- 2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H- cyclopental[a]phenanthren-17-yl)pentanoic acid

  • Molecular formula

    C24H40O4

  • Molecular weight

    392.58

  • Structure

Xylazine
  • INN

    Xylazinum

  • Therapeutic use

    Sedative, analgesic, muscle relaxant (vet.)

  • Quality application

    USP VMF Complete Document, USP ASMF (Active Substance Master File)

  • CAS number

    7361-61-7

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine

  • Molecular formula

    C12H16N2S

  • Molecular weight

    220.34

  • Structure

Xylazine hydrochloride
  • INN

    Xylazini hydrochloride

  • Therapeutic use

    Sedative, analgesic, muscle relaxant (vet.)

  • Quality application

    Ph.Eur. CEP (Certificate of Suitability) Ph.Eur. ASMF (Active Substance Master File) USP ASMF (Active Substance Master File)

  • CAS number

    23076-35-9

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine hydrochloride

  • Molecular formula

    C12H16N2S • HCl

  • Molecular weight

    256.80

  • Structure

Zopiclone
  • INN

    Zopiclone

  • Therapeutic use

    Hypnotic

  • Quality application

    Ph.Eur. CEP (Certificate of Suitability) Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    43200-80-2

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    4-methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4b]-pyrazin-5-yl este

  • Molecular formula

    C17H17ClN6O3

  • Molecular weight

    388.81

  • Structure